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An Intein-based Strategy for the Production of Tag-free Huntingtin Exon 1 Proteins Enables New Insights into the Polyglutamine Dependence of Httex1 Aggregation and Fibril Formation - ScienceDirect
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Evaluating the concordance of N-terminal and full length Huntington's disease modifiers and identifying potential therapeutic targets in Drosophila | Semantic Scholar
TNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNFα/TNFR1 signalling regulation in the pathophysiology of TRAPS | Scientific Reports
Application of CRISPR-Cas9-Mediated Genome Editing for the Treatment of Myotonic Dystrophy Type 1: Molecular Therapy
Targeting strategy for SP-D gene disruption and confirmation of the... | Download Scientific Diagram
Insects | Free Full-Text | CRISPR/Cas9-Mediated Mutagenesis of Abdominal-A and Ultrabithorax in the Asian Corn Borer, Ostrinia furnacalis
RNA toxicity in non‐coding repeat expansion disorders | The EMBO Journal
Genes | Free Full-Text | Antisense Transcription across Nucleotide Repeat Expansions in Neurodegenerative and Neuromuscular Diseases: Progress and Mysteries
Suppression of toxicity of the mutant huntingtin protein by its interacting compound, desonide | PNAS
Investigation of CAR lentiviral integration sites and TET2 dysfunction... | Download Scientific Diagram
Insects | Free Full-Text | CRISPR/Cas9-Mediated Mutagenesis of Abdominal-A and Ultrabithorax in the Asian Corn Borer, Ostrinia furnacalis
Genes containing hexanucleotide repeats resembling C9ORF72 and expressed in the central nervous system are frequent in the human genome - ScienceDirect
A cell cycle-independent, conditional gene inactivation strategy for differentially tagging wild-type and mutant cells | eLife
Site‐Specific Phosphorylation of Huntingtin Exon 1 Recombinant Proteins Enabled by the Discovery of Novel Kinases - Chiki - 2021 - ChemBioChem - Wiley Online Library
HAP40 is a conserved central regulator of Huntingtin and a potential modulator of Huntington's disease pathogenesis | PLOS Genetics
TNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNFα/TNFR1 signalling regulation in the pathophysiology of TRAPS | Scientific Reports
Dynamics of the Proline-Rich C-Terminus of Huntingtin Exon-1 Fibrils. - Abstract - Europe PMC
Flanking sequences profoundly alter polyglutamine toxicity in yeast | PNAS